By Isaac S. Kohane, Alvin Kho, Atul J. Butte
Sensible genomics--the deconstruction of the genome to figure out the organic functionality of genes and gene interactions--is the most fruitful new parts of biology. The starting to be use of DNA microarrays permits researchers to evaluate the expression of tens of hundreds of thousands of genes at a time. This quantitative swap has ended in qualitative growth in our skill to appreciate regulatory methods on the mobile level.This publication offers a scientific advent to using DNA microarrays as an investigative software for sensible genomics. The presentation is applicable for readers from biology or bioinformatics. After proposing a framework for the layout of microarray-driven sensible genomics experiments, the e-book discusses the principles for examining microarray facts units, genomic data-mining, the construction of standardized nomenclature and knowledge types, scientific purposes of practical genomics examine, and the way forward for practical genomics.
Read Online or Download Microarrays for an Integrative Genomics, 3rd edition (Computational Molecular Biology) PDF
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