By Cheng-Chiu Huang, Gabriella D’Arcangelo (auth.), S. Hossein Fatemi M.D., Ph.D. (eds.)

Reelin glycoprotein is an enormous secretory protein with vital roles in embryogenesis and through grownup existence. Reelin gene mutations or deficiency of the protein product reason irregular cortical improvement and reelin signaling impairment in mind. because the first discovery of the reelin mutant mouse in 1951 by way of Falconer, and later discovery of the gene for reelin in 1995, there was an explosion of recent wisdom approximately this significant molecule. Reelin Glycoprotein: constitution, Biology and Roles in healthiness and Disease, written by way of a world panel of specialists, summarizes the nation of the information on quite a few facets of reelin. subject matters comprise the reelin gene and its receptors, downstream effector molecules in reelin signaling cascade, chemistry and constitution of reelin, comparative anatomy of reelin, presence of reelin in a number of physique tissues, reelin mutations, and abnormalities of reelin creation in neuropsychiatric issues and melanoma. This publication will function a origin for research of this rising novel protein for all neuroscientists and clinicians.

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